Do artificial sweeteners help you live longer? A new umbrella review tried to reconcile why RCTs and observational studies have seemed to disagree. Many epidemiological studies show an increased risk of mortality, CVD, obesity, type 2 diabetes, and cognitive decline with artificial sweetener intake, but the shorter human randomized controlled trials show that artificial sweeteners tend to reduce body weight and improve glycemic control. So why do the studies disagree? It boils down to study desi