Prevent Clostridium difficile Infection (C. diff) C. difficile is a bacteria that can cause severe diarrhea and colitis, especially after antibiotic use. You can reduce your risk by: • Using antibiotics only when necessary – avoid unnecessary or prolonged courses. • Practicing good hand hygiene – wash hands thoroughly with soap and water. • Cleaning surfaces properly – especially in hospitals or care settings. • Seeking prompt medical care if you develop watery diarrhea after antibiotics. Antibi