5 days ago · A Mississippi River cruise offers the rare opportunity to sail through America's heartland on the world’s #1 river cruise line. Explore picturesque towns and boom cities; take in views of pastoral farms and towering bluffs; and immerse yourself in the region's rich history and culture with an included excursion in every port.

5 days ago · Revel in the charm of “America’s Great River” as you set sail along the Mississippi. Admire the historic mansions and grand homes atop its bluffs, and delve into America’s Civil War history. Delight in the region’s famed Southern cuisine and sample Memphis’s renowned barbecue, alongside artisan beers.

Purpose-built for the Mississippi, the ship’s cutting-edge design, expansive windows and comfortable amenities make it the first truly modern cruise ship in the region. Only 386 guests; Crew: 147; Length: 450 feet; Beam: 75 feet; Class: river ship; Year built: 2022

5 days ago · Discover Darrow, the gateway to the grand homes of the Lower Mississippi, and explore the fascinating towns along the banks of the Mississippi that preserve the memory of the American South’s early history.

5 days ago · Cruise America’s Great River History and culture unfold as you traverse the Mississippi on this enriching voyage. Enjoy relaxing scenic sailing and unparalleled bird-watching as the landscape changes between the bluffs of the North and the bayous of the South.

Stretching for 2,350 miles down the United States, from Minnesota's Lake Itasca to the Gulf of Mexico, our new cruises on the "Mighty Mississippi" offer a different type of cross-country journey for the curious explorer—one that allows you to be immersed in American history and culture.

Explore the world's most scenic rivers with Viking’s river cruises. Discover award-winning itineraries, elegant small ships and immersive experiences. Book your unforgettable river cruise today!

Cruise NEW! Mississippi River Odyssey Revel in the charm of “America’s Great River” as you set sail along the Mississippi. Admire the historic mansions and grand homes atop its bluffs, and delve into America’s Civil War history.

5 days ago · Enjoy the view as your ship navigates through the river’s intricate lock system and experience the region’s many cultural treasures—from ragtime, polka and Norwegian folk music to Wisconsin cheese, craft beer and hearty stews. https://aem-prod-publish.viking.com/content/dam/vikingcruises/en/magnolia-images/river/cruises/heartland-of ...

Get available dates and pricing for Heartland of America river cruises. Book your 2025 St. Louis (Alton) to St. Paul river cruise through Viking Cruises.