In this article, we'll look at a few of the most important core cell cycle regulators: proteins called cyclins, enzymes called Cdks, and an enzyme complex called the APC/C.

Learn about mechanisms of cell cycle regulation and the major cell cycle checkpoints.

The cell cycle is tightly regulated by checkpoints between the G1 and S phase, and between the G2 and mitosis. Key proteins, cyclin-dependent kinases and cyclins, control this process. Cyclins are …

Examine the role of cell-cell junctions in facilitating communication and maintaining tissue integrity. Discover how signaling pathways regulate responses and support survival in diverse biological …

How cells use checkpoints at the end of G1 phase, end of G2 phase, and partway through M phase (the spindle checkpoint) to regulate the cell cycle.

In most cases, these changes in activity are due to mutations in the genes that encode cell cycle regulator proteins. Here, we’ll look in more detail at what's wrong with cancer cells. We'll also see …

Analyze how the cell cycle is regulated and identify what happens when those controls break down. Investigate how disruptions in checkpoints and signaling pathways can lead to uncontrolled cell …

Cells perform these tasks in an organized, predictable series of steps that make up the cell cycle. The cell cycle is a cycle, rather than a linear pathway, because at the end of each go-round, the two …

From oocyte maturation to the in vitro cell cycle: the history of discoveries of Maturation-Promoting Factor (MPF) and Cytostatic Factor (CSF) [De la maduración de oocitos al ciclo celular in vitro: la …

The cell cycle is usually regulated by checkpoints. These are the factors that a cell considers when deciding whether or not to move forward through the cell cycle, and include both external cues (like …