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YAQ006 and YAQ007 are, respectively, the intravenous and oral formulations of L-ornithine phenylacetate (L-OPA), a potent ammonia-scavenging agent. Yaqrit is preparing to start a phase 3 trial ...

A decrease in VLCFA levels in brain, the main tissue affected in X-ALD, is likely because it has been shown that phenylacetate, the initial product of 4PBA breakdown, can cross the blood–brain ...

Sandra A. Banta-Wright, MN, RNC, NNP; Robert D. Steiner, MD Neonates with profound and prolonged hyperammonemia with coma due to urea cycle defect will have had a neurological insult to the brain ...

Background: Musk is a blackish-brown solid used in traditional Chinese medicine with a unique and intense scent. Limited evidence on its function and pathways is available from databases due to the ...