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Neomycin can be used alone or in combination with bacitracin, polymyxin, antifungals, and corticosteroids (Marks et al., 2002). The first report of an allergy to neomycin occurred in 1952 (Gehrig ...
Neomycin and bacitracin will be discussed in further detail. The North American Contact Dermatitis Group found neomycin sensitivities affected 10% of all patients who were patch tested in 2005–2006.
A facile synthetic protocol for the production of neomycin B derivatives with various modifications at the 5′′ position has been developed. The structural activity relationship (SAR) against ...
Colistin and polymyxin B are effective treatment options for Gram-negative resistant bacteria but are used as last-line therapy due to their dose-limiting nephrotoxicity. A critical factor in ...