The 49ers kick off their season on the opening Monday Night Football of the campaign ... Here's everything you need to know ahead of San Francisco 49ers vs. Minnesota Vikings.

Watch the top moments from the ManningCast during the matchup between the San Francisco 49ers and Minnesota Vikings on "Monday Night Football" in Week 7 of the 2023 NFL season. Former defensive ...

The Detroit Lions are a 3.5-point road favorite over the San Francisco 49ers at FanDuel ... Win or lose, the Lions are playing the Minnesota Vikings next week for the NFC North crown and the ...

Minnesota's 27-25 victory over ... The Detroit Lions are 3.5-point favorites over the San Francisco 49ers in the final Monday Night Football contest of the 2024-25 NFL season.

Former head coach Bill Belichick breaks down the the Los Angeles Rams' opening drive touchdown against the Minnesota Vikings on the ManningCast during "Monday Night Football" during Wild Card ...

San Francisco 49ers host the Detroit Lions on Monday Night Football to disrupt the Lions' quest for the NFC's No. 1 seed. The San Francisco 49ers and Detroit Lions reignite their rivalry under the ...

Monday Night Football makes one final appearance this season as the NFL wild card playoff schedule wraps up tonight. Here's what you need to know about Monday Night Football, the NFL divisional ...

The Trent Williams holdout is over; San Francisco 49ers now at full strength ... and 49ers is scheduled to kick off at 8:20 p.m. ET on Monday at Levi's Stadium.