eLife3y
Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS–Hook–FHIP complexes
In eukaryotic cells, intracellular components are organized by the microtubule motors cytoplasmic dynein-1 (dynein) and kinesins, which are linked to cargos via adaptor proteins. While ~40 kinesins ...
Frontiers6y
Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans
Washed particles were coupled with DQ Green-BSA (Life Technologies, Carlsbad, California, USA) and 100 μg IgG (Sigma-Aldrich) in coupling buffer (0.1 M boric acid in double distilled water, adjusted ...
eLife12y
A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network
Planar cell polarity (PCP) requires the asymmetric sorting of distinct signaling receptors to distal and proximal surfaces of polarized epithelial cells. We have examined the transport of one PCP ...