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Epidemiology of childhood interstitial lung disease in France: the RespiRare cohort

Introduction Interstitial lung disease in children (chILD) are rare and mostly severe lung diseases. Very few epidemiological data are available in limited series of patients. The aim of this study ...
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Neutrophils and tissue damage: is hypoxia the key to excessive degranulation?

Correspondence to Professor Rachel C Chambers, Centre for Inflammation and Tissue Repair, Division of Medicine, University College London, London WC1E 6JF, UK; r.chambers{at}ucl.ac.uk ...
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Fragmentation of care between intensive and primary care settings and opportunities for improvement

Correspondence to Nina Leggett, Department of Critical Care, The University of Melbourne, Parkville, Victoria, Australia; nleggett{at}student.unimelb.edu.au; A/Prof Kimberley Joy Haines; ...
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Comparative safety of inhaled medications in patients with chronic obstructive pulmonary disease: systematic review and mixed treatment comparison meta-analysis of randomised ...

3 Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan Correspondence to Dr Mei-Shu Lai, Graduate Institute of Epidemiology and Preventive Medicine, College of Public ...
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Association between maternal asthma and impaired infant lung function is diminished by inhaled corticosteroid use in pregnancy

Background Infants of asthmatic mothers have reduced lung function in early life for reasons that remain to be defined. The association between inhaled corticosteroid (ICS) use during pregnancy and ...
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Thrombocytosis is associated with increased short and long term mortality after exacerbation of chronic obstructive pulmonary disease: a role for antiplatelet therapy?

Introduction Evidence suggests that platelets play a significant role in inflammation in addition to their role in thrombosis. Systemic inflammation is linked to poor short and long term outcomes in ...
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Inhaled mannitol for non-cystic fibrosis bronchiectasis: a randomised, controlled trial

10 Hospital Interzonal Especializado en Agudos y Cronicos "Dr Antonio A. Cetrangolo”, Partido de Vicente Lopez Provincia de Buenos Aires, Buenos Aires, Argentina Rationale Bronchiectasis is ...
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Coronary artery calcification is increased in patients with COPD and associated with increased morbidity and mortality

12 Department of Respiratory Medicine, Odense University & University of Southern Denmark, Denmark/University of Manchester, Academic Health Science Centre, Manchester, UK 13 Department of Respiratory ...
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Pneumococcal serotypes in adult non-invasive and invasive pneumonia in relation to child contact and child vaccination status

2 Respiratory and Systemic Infection Laboratory, Public Health England, Microbiology Services Division, London, UK 3 Public Health England East Midlands, Derbyshire and Nottinghamshire Health ...
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The Clinical COPD Questionnaire: response to pulmonary rehabilitation and minimal clinically important difference

Background The Clinical COPD Questionnaire (CCQ) is a simple 10-item, health-related quality of life questionnaire (HRQoL) with good psychometric properties. However, little data exists regarding the ...
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Sarcopenia in COPD: prevalence, clinical correlates and response to pulmonary rehabilitation

Background Age-related loss of muscle, sarcopenia, is recognised as a clinical syndrome with multiple contributing factors. International European Working Group on Sarcopenia in Older People (EWGSOP) ...