Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

Responsive photonic crystals assembled from colloidal particles have been increasingly utilized in detection and sensing devices owing to their attractive ability to change color in response to ...

Genome editing is a crucial technology for obtaining desired phenotypes in a variety of species, ranging from microbes to plants, animals, and humans. With the advent of CRISPR-Cas technology, it has ...

The complete biosynthetic pathways of the potent antifungals AS2077715 (1) and funiculosin (2) are reconstituted and characterized. A five-enzyme cascade, including a multifunctional flavin-dependent ...

Keratinases is a special hydrolytic enzyme produced by microorganisms, which has the ability to catalyze the degradation of keratin. Currently, keratinases show great potential for application in many ...

In the past decade, traditional fuel vehicles have gradually been replaced by electric vehicles (EVs) to help reduce the consumption of fossil fuels and the emissions of greenhouse gases, and lithium ...

The field of bioelectronics leverages the optoelectronic properties of synthetic materials to interface with living systems. These applications require materials that are conductive, ...

Recently, organic semiconductor-incorporated perovskites (OSiPs) have emerged as a new subclass of next-generation organic–inorganic hybrid materials. OSiPs combine the advantages of organic ...

Facilities operated by the US Department of Energy (DOE) are required to have extensive worker safety and health programs by regulation. We describe how Argonne National Laboratory (ANL) has ...

Molecular electronics is a field that explores the ultimate limits of electronic device dimensions by using individual molecules as operable electronic devices. Over the past five decades since the ...

Fluorine and nitrogen form a successful partnership in organic synthesis, medicinal chemistry, and material sciences. Although fluorine-nitrogen chemistry has a long and rich history, this field has ...

Synthetic biology has played an important role in the renaissance of natural products research during the post-genomics era. The development and integration of new tools have transformed the workflow ...