While the infralimbic cortex (IL) is recognized as critical for behavioral inhibition, the content of the inhibitory memories stored in this region remains elusive. To probe this content, we examined ...

Comprehensive residue-level mapping of amyloid-beta recognition reveals how sequence variants, post-translational ...

Experiments mapping individual neurons in the sensorimotor cortex of mice show that sharp transitions in functional ...

Drug repurposing analyses show that citalopram exerts anti-tumor effects by targeting C5aR1 on tumor-associated macrophages to enhance phagocytosis and CD8+ T cell immunity.

Mouse primary motor and somatosensory cortices contain detailed information about the many time-varying arm and paw joint ...

The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

Muscle stem cells repurpose the tenogenic factor Scx to establish a muscle-specific transcriptional program that sustains stem cell expansion, migration, differentiation, fusion, self-renewal, and ...

Upregulated expression of transcription factors promoting cone identity in late-stage retinal progenitors drives development ...

Mir195 enables Ebf1-deficient hematopoietic progenitor cells to mature into B cells, suggesting some miRNA can substitute for transcription factors in differentiation.

eLife reviews research covering virology, bacteriology and mycology. Learn more about what we review and sign up for the latest research.