While extremely rare, encephalopathy (a condition affecting brain function) triggered by mutations in the UBA5 gene has ...

While extremely rare, encephalopathy (a condition affecting brain function) triggered by mutations in the UBA5 gene has devastating impacts, with affected individuals reaching few developmental ...

Since the opening of their first hospital in 1922, Shriners Children’s has provided pediatric specialty care and helped thousands of kids live their best lives. Now you can be a part of ...

Compared with placebo, ATH434 demonstrated a statistically significant 48% slowing of clinical progression (based on UMSARS score) at the 50mg dose at week 52. The Food and Drug Administration ...

Gemma Illingworth, from Manchester, was diagnosed with posterior cortical atrophy (PCA), a rare form of dementia, in 2021, while working from home during the pandemic. She died in November last ...

Alterity's previous interactions with the FDA indicated that the modified Unified Multiple System Atrophy Rating Scale (UMSARS) Part I scale is considered a clinically meaningful endpoint for MSA.

Astellas has suffered another major setback with geographic atrophy (GA) treatment Izervay, this time in the US. The company has received a complete response letter (CRL) from the FDA for a ...

Astellas confirmed today that it will withdraw its EMA filing for avacincaptad pegol as a treatment for eye disorder geographic atrophy (GA), based on feedback from the EU regulator. It is a major ...

Researchers presented an exploratory analysis comparing OCT biomarkers in a Phase 1b study of ONL1204 in patients with ...

Further cognitive testing showed a pattern of intact cortical functions but clear evidence of subcortical and frontal lobe dementia, consistent with the diagnosis of alcoholic dementia.

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a long-term neurological disorder that targets your body’s nerves. Anyone can get CIDP, but it’s most common in older adults and ...