So, we have A beta monomer, we have A beta oligomer, we have A beta protofibrils, and then plaques. And so, these different aggregated monomeric or aggregated forms, have different physiological ...

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relative to Aβ monomers and amyloid plaques. Soluble AβOs have been observed to be potent neurotoxins that bind to neurons, inhibit synaptic function and induce neurodegeneration. By selectively ...

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