Neomycin and bacitracin will be discussed in further detail. The North American Contact Dermatitis Group found neomycin sensitivities affected 10% of all patients who were patch tested in 2005–2006.

Only the neomycin-bacitracin-polymyxin B combination effectively eliminated the bacterial contamination of the wounds, after two applications within 16 to 24 hours after contamination with S. aureus.

A facile synthetic protocol for the production of neomycin B derivatives with various modifications at the 5′′ position has been developed. The structural activity relationship (SAR) against ...

Colistin and polymyxin B are effective treatment options for Gram-negative resistant bacteria but are used as last-line therapy due to their dose-limiting nephrotoxicity. A critical factor in ...