An effective HIV-1 vaccine must therefore elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies (bnAbs) have been isolated from HIV-1 infected ...

RT-associated RDDP and RNase H functions are essential for HIV-1 genome replication. Among the HIV-1 RT inhibitors ... determining pan-assay interference compounds, analysis of structure–activity ...

HIV-1 particles are released from infected cells in an immature ... For many years, scientists have explored the structural changes of the virus capsid which encases the genome. In contrast, much less ...

Schematic representation of HIV-1 genome organization. The three coding reading frames are depicted along with their open reading frames (rectangles). Genome position is numbered according to HXB2 ...

He Jiankui stands by a controversial research approach that landed him in prison as he aims to tackle Alzheimer’s disease.

An arms race is unfolding in our cells: Transposons, also known as jumping genes or mobile genetic elements as they can replicate and reinsert themselves in the genome, threaten the cell's genome ...

In this interview, Dr. Christian Schafmeister discusses the structural advantages of Spiroligomer molecules, their ability to ...

Research in the HIV-1 field is no exception: the challenges encountered in ... Sonication produces random DNA cleavage sites across the host genome. Linker primers are ligated to provide a template ...

Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir ...