SportsLine's model simulated Los Angeles Rams vs. San Francisco 49ers 10,000 times and made its Week 3 NFL picks, predictions ...

Preview the Week 3 matchup between the San Francisco 49ers and Los Angeles Rams with predictions, odds, over/under, spread, ...

With Christian McCaffrey already on the injured reserve, Deebo Samuel has been ruled out due to injury for Week 3 in Los ...

Injuries stacked up quickly for the San Francisco 49ers leading up to their Week 3 showdown with the Los Angeles Rams.

The San Francisco 49ers will likely be without All-Pro tight end George Kittle for Sunday’s game against the Los Angeles Rams ...

Sean McVay shared injury updates ahead of Sunday’s game, already ruling out two players and listing three as questionable ...

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West ...

Kyle Shanahan is considered one of the smartest offensive coaches in the NFL, but according to former NFL coach Jay Gruden, ...

Brock Purdy has faced the Vikings twice in his career. In both games, he turned the ball over twice, led the 49ers to just 17 ...

San Francisco 49ers quarterback Brock Purdy will be tested in the coming weeks with the absence of key offensive weapons.

The San Francisco 49ers are officially listing tight end George Kittle as doubtful to play for their Week 3 divisional ...

According to Tallysight, a whopping 96% of experts are picking the 49ers to beat the Rams. It’s slightly better when ...