A 45-nucleotide strand of RNA can now synthesize both its mirror-image complement and a copy of itself, bringing scientists ...
We the authors are retracting this Article because our efforts to repeat and follow up on the results have been unsuccessful. Specifically, we have been unable to reproduce observations suggesting ...
Antisense oligonucleotides (ASOs) are small, single-stranded molecules that can suppress the expression of targeted genes and thereby achieve therapeutic effects. However, many ASO-based drug ...
Researchers at the MRC Laboratory of Molecular Biology in Cambridge have discovered a ribozyme that is shockingly small, yet ...
Researchers from Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, USA, report a modification wherein replacing the RNA strand of a heteroduplex oligonucleotide with DNA may ...
Antisense oligonucleotides (ASO) hold great promise for pharmacotherapy. Now, researchers at Tokyo Medical and Dental University (TMDU) and Ionis Pharmaceuticals, advancing their earlier work on a ...
Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...
Scientists from the Skoltech Center for Life Sciences (CLS) led by professor Dmitri Pervouchine and their colleagues from Russian and international laboratories used molecular and bioinformatics ...
Adenine was first discovered in 1885 by the German physiologist Albrecht Kossel. He isolated adenine from the pancreas of oxen and named it "adenine" derived from the Greek word "aden," meaning gland.
Researchers in China have developed a new method that allows them to insert long stretches of DNA into a genome. The process, named GRAND editing, is one of a handful of new systems aimed at using two ...
In this free webinar, learn how innovative long RNA manufacturing approaches can drive the development of next-generation RNA medicines. Attendees will understand the limitations of current methods ...