Every time a cell divides to produce two new daughter cells., the genome must be replicated and evenly divided between those ...

For chromosomes to form the iconic X-shape that ensures the accurate passing of genetic information during cell division, a ...

An international team of researchers co-led by Job Dekker, Ph.D., at UMass Chan Medical School, have identified rules that ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have ...

How is all of that DNA packaged so tightly into chromosomes and squeezed into a tiny nucleus? Histones are a family of small, positively charged proteins termed H1, H2A, H2B, H3, and H4 (Van Holde ...

For this, the cell must duplicate its DNA—its genome—and segregate it equally into two new daughter cells. To prepare the 46 chromosomes of a human cell for transport to the daughter cells ...

DNA strand displacement circuits are inching closer to becoming cellular machines. Scientists are finding ways to make these ...

A new study has shown how chromosomes change shape during cell division. Certain protein complexes help fold DNA into overlapping loops that repel each other, which then stack to create a rod-like ...

Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for innovative therapeutic strategies.

Cells use many complex genetic repair backup systems to fix DNA damage and remain healthy throughout their lives.

They exist as circular pieces of DNA in the nuclei of tumor cells outside chromosomes ... The ecDNAs can be tethered into clusters (called hubs) that enable dynamic interactions among their ...