It’s a kind of control that no one has ever tried before in patients,” Tune’s chief scientific officer said Monday.

A Durham biotech firm founded on technology built at Duke University has raised $175 million to fund clinical trials of its treatment that tunes gene activity within the body. Why it matters: The fundraising round by Tune Therapeutics is one of the largest in the Triangle in recent months and will give the company runway to collect more data on its leading drug,