The actress, who stars alongside Demi Moore in the body horror film, says it took "probably a year" for her skin to recover.

Margaret Qualley says her skin went through a lot while filming 'The Substance.' On Josh Horowitz’s 'Happy Sad Confused' podcast, the actress opened up about the effects of wearing prosthetics for the film and how it impacted her skin.

The Substance costume designer Emmanuelle Youchnovski revealed in an interview with Next Best Picture that one of Margaret Qualley’s outfits as Sue in the Golden Globe-nominated body horror masterpiece was inspired by the “Houdini” singer, as well as Beyoncé.

The actress recalled what it was like working with prosthetics for her role in the body horror film, which also stars Demi Moore.

Margaret Qualley is opening up about the long-lasting effects she suffered while filming for 'The Substance.' The actress, who plays Sue in the body horror film, recently shared on the Happy Sad Confused podcast that her skin was damaged for nearly a year after filming wrapped.

Adhesive materials, artificial skin, and layers of heavy makeup used to create these effects can often clog pores

"It took me probably, like, a year to recover physically from all of it," she told a podcast about the prosthetics used in the film.

During a recent appearance on the Happy Sad Confused podcast, Margaret Qualley revealed that the prosthetics she wore in "The Substance" "f--ked up" her skin, saying that it took "a year" for her skin to fully recover from the acne.

In The Substance, Margaret Qualley's character turns into an overnight superstar. So naturally, the film's costume director Emmanuelle Youchnovski turned to some real-life idols for inspiration - including Beyoncé and Dua Lipa.