In a recent study posted to the medRxiv* preprint server, researchers assessed whether loss-of-function (pLOF) variants of type I interferon (IFN) immunity genes are associated with life-threatening ...
SARS-CoV-2 variants of concern and the biological sex of patients affect the efficacy of molnupiravir, the first orally available drug approved for outpatient use against COVID-19, according to a new ...
A prospectively maintained database at an academic medical center was used to identify individuals with SDHx PVs. The research team abstracted demographics, clinical, genomic, and variant information ...