Transcription factor binding sites may help explain underlying causes of many diseases
A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...
Nature1y
Do Transcription Factors Actually Bind DNA? DNA Footprinting and Gel Shift Assays
A typical footprinting experiment involves radioactive labeling of the DNA region of interest—usually a larger chunk of DNA suspected to contain one or more transcription factor binding sites.
Nature4y
Discovery of putative transcription factor binding sites from microarray-based gene expression profiles
Among the highest rating patterns most have matches to substrings in known yeast transcription factor binding sites. Moreover, several of them are known to be relevant for the expression of the ...
eLife18d
Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa
The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...