Transcription factor binding sites may help explain underlying causes of many diseases
A multi-institutional team of investigators have developed a catalog of transcription factor binding sites that regulate gene ...
Nature1y
Do Transcription Factors Actually Bind DNA? DNA Footprinting and Gel Shift Assays
A typical footprinting experiment involves radioactive labeling of the DNA region of interest—usually a larger chunk of DNA suspected to contain one or more transcription factor binding sites.
Nature7y
transcription factor / transcription factors
One distinct feature of transcription factors is that they have DNA-binding domains that give them ... sequence near the transcription start site and help form the transcription initiation complex.
eLife10d
Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa
The transcription factor regulatory network in Pseudomonas aeruginosa is complex and involves multiple regulators that respond to various environmental signals and physiological cues by regulating ...