Researchers have discovered a biosynthetic pathway that makes amino acids containing terminal alkynes. Because such functional groups are rare in natural products, they provide a handle for chemistry ...
Alkynes are prized among chemists for their uniquely reactive carbon-carbon triple bonds, which make them excellent coupling partners in click chemistry, for example. Now, chemists at the University ...
Dehydrogenative silylation of terminal alkynes represents a pivotal strategy in organosilicon chemistry, enabling the direct installation of silyl groups onto acetylenic substrates through the formal ...
The catalytic asymmetric synthesis of alkynes and enol esters encompasses a suite of methods that employ chiral transition-metal complexes to forge carbon–carbon triple bonds and install ester ...