By mapping protein interactions in biofluids, researchers gained new insights into alpha-synuclein’s role in Parkinson’s ...
Misfolded α-synuclein is heavily implicated in the pathogenesis of Parkinson's disease. In its native state, α-synuclein is widely believed to be a 14-kDa unfolded monomer. Selkoe and colleagues now ...
A review discusses what immunotherapies are currently being evaluated to target α-synuclein, an abnormal protein suggested to have a central role in the pathogenesis of PD. Parkinson disease (PD) is ...
New York, USA, Feb. 13, 2025 (GLOBE NEWSWIRE) -- Alpha-Synuclein Inhibitors Clinical Trial Pipeline as Novel and Extensive 22+ Therapies Likely to Enter in the Domain | DelveInsight Alpha-synuclein ...
Misfolding and aggregation of normally soluble proteins are common pathological features of many neurodegenerative diseases, including Alzheimer's, Parkinson's, Creutzfeldt-Jacob and Huntington's ...
Neuropacs™ Corp., a leader in AI‑powered neurodiagnostics, today announced the publication of a seminal study co-authored by David Vaillancourt, PhD, the company’s Co‑Founder and Chief Scientific ...
The so-called isolated REM-sleep behavior disorder is a condition that can provide an indication of Parkinson's disease well in advance. A research team headed by Professor Dr Erdem Gültekin Tamgüney ...
[Editor’s note posted 7 March 2025: The Larson et al paper covered in this news story has been retracted.] Alzheimer’s disease is usually thought of as a disorder of two proteins, Aβ and tau, but ...
There are two forms of Parkinson’s disease (PD). In 70% of cases, it originates in the central nervous system. However, in around 30% of cases, it originates in the nervous system of the intestine ...
A new double-transgenic mouse may provide a good model for Lewy-body diseases and offer insight into mechanisms that underlie Alzheimer's and Parkinson's disease. Eliezer Masliah and colleagues at ...
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