Recent decades have seen ever louder calls for improved study design and reproducibility standards in animal research. This stems from wider discussions across the scientific community about the ...

Jay Bhattacharya dismissed the test-negative design as 'crap.' The biostatistics literature tells a different story.

Once you have determined your research question, the next step is to decide on a research design. As random assignment tends to be challenging in SoTL, most projects tend to fall into the ...

Resources for observational comparative research have expanded enormously in recent years to include very large sources of ...

Good experiments start with good planning. The analysis of genetic and molecular information involves increasingly sophisticated tools and methodologies, many of which are advancing at a fast pace.

Noninferiority clinical trials have become a major tool for the evaluation of drugs, devices, biologics, and other medical treatments. Treatment with placebo or with a no-treatment control in a study ...

Cohort studies are a type of research design. They are also called longitudinal studies because they follow groups of people over time. Results from cohort studies can help people understand human ...