Here, we demonstrate the utility of the signal strapping method by identifying four metalloprotein families, each of which displays diverse 3-dimensional folds, distinct from that the classical LPMOs.

Signal peptide peptidase-like (SPPL) proteases, members of the intramembrane aspartyl protease family, have attracted increased interest due to their involvement in immune cell differentiation and ...

Drug development and production rely on stringent quality controls, reproducibility, and verification. Biopharmaceuticals, including protein-based therapies, require extensive characterization, ...