Post-translational modifications (PTMs) play a key role in dynamic cellular processes, regulating gene expression, protein activity, localization, and degradation, as well as protein interaction.

The amino acid side chains of proteins undergo various post-translational modifications (PTMs) which significantly impact protein function and mediate complex cellular events. Measuring the dynamics, ...

The focus of vertebrate studies has mainly been on canonical phosphorylation, but research indicates that phosphorylation of other non-canonical amino acids also regulates integral aspects of cell ...

Being bullied leaves a biochemical footprint in the brain. Protein lactylation is a very recently discovered post-translational modification of protein that involves the addition of a lactyl group to ...

Post-translational modifications (PTMs)—the chemical changes that proteins undergo following biosynthesis—account for most protein forms, or proteoforms. Indeed, according to conservative estimates, ...

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein binds the host cell surface receptor angiotensin-converting enzyme 2 (ACE2). It is a glycosylated protein and is a target ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Emerging mass spectrometry technologies integrating ion mobility, TIMS–PASEF, and real-time search are enhancing sensitivity, ...

Promise Bio, a company pioneering precision medicine solutions using epiproteomics and artificial intelligence, today announced the launch of the Frontier Epiproteomic Innovation Grant, an R&D access ...

Explore the evolution of clinical proteomics in modern medicine. Discover how advanced protein analysis transforms biomarker ...