Podocytes respond to hormones and growth factors that are present in the circulation or locally produced in the glomerulus A variety of receptors on the cell surface are thought to enable podocytes to ...

A new research paper titled "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span" has been published in Aging. The decrease in the podocytes' lifespan and health span ...

Unlike other human stem cells, Induced pluripotent stem cells (iPS cells) can be produced directly from adult cells. Now, researchers have shown that human kidney podocytes produced from iPS cells via ...

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the ...

Although the pathophysiology of mesangial cells has long been considered to be the major factor in the development of glomerulosclerosis in type 1 or type 2 diabetes, more recent evidence suggests ...

A newly-established protocol offers hope for kidney disease modeling, drug discovery, and potential cell therapies. Previous work from the Wyss Institute at Harvard University established a protocol ...

BUFFALO, N.Y. — In the early stages of kidney disease, a specialized type of kidney cell called the podocyte undergoes damaging changes in both its structure and function. Those changes are key ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, “Inhibiting NLRP3 signaling in aging ...