Scientists have discovered a hitherto unknown function of blood platelets in cancer. In mouse models, these platelets have proved to help preserve the vascular barrier which makes blood-vessel walls ...

Study of the bleeding tendency in uremia in 26 subjects, 10 of whom were bleeding, showed platelet counts and plasma coagulation factors to be normal. There was a significant inverse correlation ...

The field of immunological tolerance increasingly highlights the multifaceted roles played by platelets far beyond their classical functions in hemostasis.

A new understanding of novel functions of platelets could lead to new treatments to reduce bleeding in trauma and severe infections. A new finding could lead to novel treatments to reduce bleeding in ...

Since the discovery of platelets approximately 160 years ago, extensive research has characterized how platelets function and clarified their role in hemostasis, thrombosis, and in a number of ...

Platelets have multiple direct and indirect functions that integrate innate and adaptive antimicrobial host defences. Platelets actively sense signals of tissue injury and microbial infection via an ...

Patients on prasugrel therapy have greater platelet inhibition than those taking maintenance doses of clopidogrel and thus require a longer time to return to baseline reactivity after stopping the ...

"Platelets are the smallest blood cells that work in clotting to heal cuts because they stick to the site of the injury," said Xia, a member of OMRF's Cardiovascular Biology Research Program. "This ...

One of the side effects of aspirin is reduced platelet function. Aspirin can potentially make issues with blood clotting worse. Thrombocytopenia is the medical term for low platelet count. Platelets ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...