In a statement, the FDA said it has authorized the marketing and sale of Philip Morris International’s Zyn nicotine pouches. The pouches, which are placed between the lip and gum, are tobacco-free but contain nicotine. They come in different strengths and a variety of flavors such as citrus, coffee, peppermint and berry.

This marketing decision from the FDA covers 2 nicotine strengths, 3 mg and 6 mg, and 10 flavors of the small tobacco-free synthetic pouches.

The Food and Drug Administration Thursday authorized marketing of 20 nicotine pouches — the first time the products have been greenlit by the agency. Nicotine pouches are tobacco-free sachets filled with nicotine and flavorings that are held between the gums and lips similar to snus,