De novo mutations are a cause of sporadic disease, but little is known about the developmental timing of such mutations. We studied concordant and discordant monozygous twins with de novo mutations in ...

The Glickman lab, in close collaboration with the Shuman lab, is broadly interested in the pathways and regulation of DNA repair in mycobacteria. Our goals in the DNA repair arena are twofold: 1) to ...

This comprehensive book covers the underlying scientific principles, state of the art technologies and methodologies of plant mutagenesis. It covers historical development and commonly used ...

During photosynthesis, an enzyme called rubisco catalyzes a key reaction—the incorporation of carbon dioxide into organic compounds to create sugars. However, rubisco, which is believed to be the most ...