A report in last week's Cell suggests that TGF-β1, one of the three mammalian isoforms of that growth factor, can protect against excitotoxic neurodegeneration, which is thought to be related to the ...

TGF-ß, which has been studied for more than 30 years, has many jobs. One of them is helping to regulate the immune system. The immunotherapy drugs called checkpoint inhibitors have transformed ...

TGF-beta may be an “old story” in the study of cancer, but a plot twist was recently encountered by scientists from the Medical University of South Carolina. TGF-beta, which is hijacked by cancer ...

A recent mouse model based study suggests that blocking TGF-β may improve osteoporosis treatment by helping quiescent osteoblasts in inactive bone surfaces return to an active state. Using spatial ...

The yin and yang of transforming growth factor β (TGF-β) is nowhere more apparent than in Alzheimer disease. It’s been known for over a decade that expression of the cytokine is increased in AD brain ...

If biology did have a motto, it may well be ‘nothing is ever as simple as it seems,’ an idea which is exemplified by today’s scientific story. It comes to us from the Prlic Lab in the Vaccine and ...

Over the past few decades, the idea of modifying a patient’s own immune cells to recognize and destroy cancer has evolved from concept to reality. So-called “adoptive T cell therapy” has emerged as ...