Levels of C4d and C4d/C4 associate with clinical and histopathological treatment response in proliferative lupus nephritis. Complement activation markers, particularly C4d and the C4d/C4 ratio, are ...

Study offers molecular explanation for long-standing observation that certain diseases occur more often or more severely in different sexes. Complement component 4 (C4) genes protect against the ...

Please provide your email address to receive an email when new articles are posted on . Kim’s hypothesis arises partially from studies that showed that C3, when introduced to synthetic neutrophils, ...

The complement system is part of the body's immune system to fight pathogens and remove cell debris; its role in two autoimmune diseases and a mental disorder is a surprise Variants in a gene of the ...

A complement C4 (also known as a complement component 4, or simply C4) is a test to measure the level of C4 proteins you have in your blood. These proteins play a role in how your immune system ...

Clinicians managing lupus nephritis should consider persistent isolated C3 as a possible indicator of long-term renal risk. Persistent isolated low C3 (PILC3) does not appear to predict short-term ...

Most people with lupus have antinuclear antibodies (ANAs) in their blood. But a positive ANA test doesn’t always mean lupus. The test can be positive in people with other autoimmune illnesses — ...

Exagen, a life science company serving the rheumatology specialty, and the Lupus Foundation of America, the national force devoted to solving the mystery of lupus, announced a new initiative to ...