The genomic instability of stem cells in culture, caused by their routine in vitro propagation or by their genetic manipulation, is deleterious both for their clinical application and for their use in ...

You have full access to this article via your institution. We captured images with video/CCD cameras or a digital camera (DP-10, Olympus), replacing the 'classic' film cameras mounted on older-model ...

Photograph of a karyotype - the collection of chromosomes within each cell of an organism - from a male mouse engineered by Johns Hopkins Medicine researchers to model Down syndrome in a human. The ...