Pulmonology Advisor

COVID-19 Vaccines: Study Compares Humoral Immune Responses of mRNA vs Ad-Vector

In a comparison of COVID-19 vaccines, the mRNA vaccine sustained higher anti-S IgG, while the Ad-vector had superior ...
The American Journal of Managed Care

Shingles Vaccine Generates Strong Immune Response in Patients With RA Receiving Upadacitinib

RA patients on upadacitinib and methotrexate showed robust antibody and T-cell responses to the recombinant zoster vaccine over 60 weeks. The vaccine maintained a satisfactory humoral response in 71.4 ...
ascopubs.org

Machine learning–driven approaches for predicting T-cell–mediated immunity and beyond.

Effect of KROS 101, a small molecule GITR ligand agonist, on T effector cells, T reg cells and intratumoral CD8 T cell cytotoxicity. Phase 1 study of DK210 (EGFR), a tumor-targeted IL2 x IL10 dual ...
ascopubs.org

MCT1-mediated histone lactylation modulates lung cancer cell sensitivity to T-cell–mediated killing by influencing mitochondrial dysfunction.

Comparison of induction chemoimmunotherapy with surgery and concurrent chemoradiation followed by immunotherapy for potentially resectable stage III non-small-cell lung cancer: A retrospective study.