The four DNA fragments (A, B, C and D) encompassing the full–length HIV–1 genome were first amplified ... California). The structure of the chimeric DNA product was verified by restriction ...
Smuggling its genome ... for HIV to infect its host, but entering the cell’s control center is no easy feat. Molecules must pass through tightly-regulated nuclear pores on the backs of specialized ...
Coauthor Yamina Bennasser and her colleagues characterized a sequence in the HIV-1 genome that encodes a rare siRNA precursor, a short hairpin RNA that is processed by the Dicer (or by a Dicer-like) ...
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Decoding HIV's tactics: RNA structures provide new insights into how virus hijacks cellsA team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of Regensburg has unveiled insights into how HIV-1, the virus responsible ...
An effective HIV-1 vaccine must therefore elicit antibodies that can neutralize many variants of the virus. While broadly neutralizing antibodies (bnAbs) have been isolated from HIV-1 infected ...
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Gilead’s capsid revolution meets our capsid solutions: Sino Biological – Engineering the tools to outsmart HIVGilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir ...
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Transposons, also known as jumping genes or mobile genetic elements as they can replicate and reinsert themselves in the ...
HIV drug susceptibility tests can evaluate either the genotype or phenotype of the predominant viral quasispecies. The HIV genotype refers to the actual DNA sequence of the virus; the phenotype ...
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