For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating-and possibly even curing-the disease a seemingly insurmountable obstacle to achieve. But ...

A stepwise HIV vaccine strategy has induced broadly neutralizing antibodies in primates, hinting that a truly protective HIV ...

A major bottleneck in curing HIV (human immunodeficiency virus) is that the virus can hide in an inactive form within resting white blood cells, which play a crucial role in coordinating the immune ...

Scientists have taken a major step toward developing an effective HIV vaccine after a new experimental vaccine successfully generated high levels of broadly ne ...

A vaccine regimen developed by La Jolla Institute for Immunology, Scripps Research and IAVI has produced substantial levels ...

Researchers at the University of Washington and Fred Hutch found that CARD8, an inflammasome sensor, detects HIV-1 in macrophages during cell-to-cell viral transmissions from infected T cells. HIV can ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

Advancements in HIV/AIDS research, drug development, and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check ...

For over three decades, HIV has played an elaborate game of hide-and-seek with researchers, making treating—and possibly even curing—the disease a seemingly insurmountable obstacle to achieve. But ...

Since the beginning of the HIV epidemic, scientists, doctors, and public health experts have spent decades trying to understand the virus and control its spread. Modern treatments now allow people ...