What about viruses? Would you consider them living or nonliving? Let’s look closely at the life cycle of the human immunodeficiency virus (HIV) – the virus that causes AIDS – to find out. This ...

Smuggling its genome ... for HIV to infect its host, but entering the cell’s control center is no easy feat. Molecules must pass through tightly-regulated nuclear pores on the backs of specialized ...

Caption: Structure of a HIV capsid (Left) Central slice view of a HIV virus-like particle with pore-forming toxin on the membrane (Middle) Atomic model of a HIV capsid (Right) Density map of HIV ...

Another important discovery was an intricate RNA structure near the critical "frameshift site" in the viral genome ... HIV-1 mRNAs are translated efficiently throughout infection, the virus ...

Paul Sharp and colleagues from the University of Nottingham Queens Medical Centre in England compared full-length genome ... residue of HIV. 1 The findings are important for two reasons: "in this ...

Such virally encoded RdRps copy the (+)-stranded genome, via an intermediate (-)-strand, for subsequent encapsidation into infectious virions. Hepatitis C virus (HCV), a (+)-strand RNA virus ...

After entering an immune cell, HIV's single-stranded RNA genome is reverse-transcribed into double-stranded DNA, which is how our cells store genetic information. The virus' genome is incorporated ...