Here, we present the case of a 27-year-old patient with HIV-1 infection and anaplastic large-cell lymphoma. Because of a poor prognosis after progression of the T-cell lymphoma, stem-cell ...

Among HIV-infected men in the MACS cohort, CXCR4-using virus emerged well before the CD3 + inflection point and the development of late-stage HIV disease. Understanding viral tropism is critically ...

Testing for HIV tropism (ie, the ability for different HIV variants to enter cells by binding to a receptor) has become an important step for clinical treatment. Genotypic and phenotypic methods for ...

At the cellular level, HIV-1 transmission involves a highly coordinated process whereby the virus binds to CD4 receptors and one of two coreceptors—CCR5 (R5) or CXCR4 (X4)—on host immune cells, ...

Please provide your email address to receive an email when new articles are posted on . The European Consensus Group released new recommendations for the clinical management of HIV-1 tropism testing, ...

CCR5-tropic virus is the predominant virus encountered, though CXCR4-tropic virus strains are more likely encountered, in patients with advanced HIV disease. Results from Phase III clinical trials ...

"Pfizer welcomes advances and innovation in tropism detection, such as the enhanced sensitivity of Trofile, which will give physicians important information when deciding whether or not to incorporate ...

Lab21 Limited announces the addition of a new diagnostic test for HIV to its portfolio of companion diagnostic services. Lab21 will be the first commercial reference laboratory in the UK to provide a ...