This article was reviewed by Felix Gussone, MD. Key Takeaways: In the U.S., testosterone is a controlled substance, so you’ll ...

Natesto (testosterone) is a prescription drug that’s used for testosterone replacement. The drug comes as nasal gel you apply to the inside of your nostrils. It’s typically used three times per day.

Advertisements for treatments for “low T,” or low testosterone levels in middle-aged and older men, have led to spikes in demand. But the safety and legitimacy of those testosterone therapies hasn’t ...