A single enzyme that can generate all four nucleoside triphosphates, the building blocks of ribonucleic acid (RNA), has been ...

CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...

Enzyme mechanisms of catalysis play many important roles in the functioning of a healthy body. An enzyme may exist as a multi-subunit complex or it may be associated with a cofactor such as adenosine ...

The mechanism by which an enzyme used in industrial production of an important drug for type-2 diabetes recognizes its target has been demonstrated by a group of researchers. This finding will further ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

The contribution of enzymes as a biological catalyst in almost all processes occurring in live organisms is significant. Studying the enzyme reactions taking place in a system, individually, is ...

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure. An international ...

It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...

Epigenetic drug discovery and development programs have attracted much attention and investment in recent years. This is driven by the potential to develop novel therapeutic strategies that can ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...