New research could pave the way to develop cancer drugs targeting an enzyme that inhibits ferroptosis, a type of cell death. Cancer cells that are resistant to anticancer drugs are known to be ...

Measuring Enzyme Kinetic Parameters with the ITC Universal Enzyme Assay Method Enzymes are important in drug discovery and development since they constitute approximately one-half of all known drug ...

This article describes a simple method to determine the optimum pH for the activity of one enzyme in a coupled enzyme assay. Decoupling of the two-step reaction is achieved by heat denaturing the ...

During the last 50 years, an abundance of data has been gathered on the function of lipids as a source of energy, as building blocks, and as signaling molecules in living systems. Lipid-signaling ...

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Overall Survival With Second-Line Pembrolizumab in Patients With Non–Small-Cell Lung Cancer: Randomized Phase III Clinical Trial Versus Propensity-Adjusted Real-World Data The ability of ...

Microbial assays are a technique to assess a compound’s potency or concentration. This is carried out by exposing microorganisms to the compound and determining its effect on them. Microbial assays ...

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