Lymphocyte development relies on the deliberate induction and precise repair of DNA double-strand breaks (DSBs) to generate the diverse repertoire of antigen receptors that underpin adaptive immunity.
LEXINGTON, Mass.--(BUSINESS WIRE)--KSQ Therapeutics, Inc. ("KSQ"), a clinical-stage biotechnology company developing cancer therapies using its proprietary CRISPRomics ® discovery platform, and CTMC, ...
Effect of BL-8040, high-affinity CXCR4 antagonist, on T-cell infiltration, tumor growth, and synergy with immunomodulatory agents. This is an ASCO Meeting Abstract from the 2017 ASCO Annual Meeting I.
CRISPR-edited tumor-infiltrating lymphocytes are emerging as a promising alternative to CAR T-cell therapy for solid cancers.
Atypical lymphocytes are types of white blood cells that a person’s immune system produces. They help fight infections and diseases. High levels of atypical lymphocytes may indicate health issues.
Dissociated Tumor Cells (DTCs) are single-cell suspensions dissociated from a solid tumor through the use of digestive enzymes and mechanical separation. This has the benefit of cryopreserving the ...