Healio

Fecal DPP-4 serves as a biomarker for ulcerative colitis, Crohn’s disease

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Fecal dipeptidyl peptidase-4 may be used as a ...
Medscape

Generic DPP-4 Inhibitors Would Be a 'Shot in the Arm'

In September, Indian drug manufacturer Alembic received a tentative nod from the US Food and Drug Administration (FDA) to manufacture generic alogliptin as well as the alogliptin/metformin fixed-drug ...
The American Journal of Managed Care

No Association Found Between DPP-4 Inhibitors and Heart Failure in Review of Claims Data

Last year, an FDA advisory panel called for an updated label for saxagliptin, but the agency is still gathering information. An analysis of claims data found no association between the use of DPP-4 ...
Healio

DPP-4 inhibitors may increase bullous pemphigoid risk in diabetes

We were unable to process your request. Please try again later. If you continue to have this issue please contact [email protected]. Dipeptidyl peptidase-4 inhibition to treat type 2 ...
Medscape

Algorithm Predicts Response to SGLT2, DPP-4 Inhibitors in Diabetes

Study results have validated that five routinely measured clinical values reliably identified patients with type 2 diabetes who had significantly different A1c responses to two important classes of ...
MedPage Today

Infographic: Incretins and More: The Physiology of DPP-4

DPP-4 exists as a membrane-bound form, widely expressed and enzymatically active on numerous cell types and different vascular beds... ...as well as a soluble form ...
MedPage Today

DPP-4 Inhibitors Tied to Blistering Skin Condition

Among people with type 2 diabetes, new treatment with a dipeptidyl peptidase 4 (DPP-4) inhibitor was linked with higher risk of a rare blistering skin condition, researchers reported. Compared with ...
The American Journal of Managed Care

Health Care Utilization Study Compares Costs of Empagliflozin, DPP-4 Inhibitors, and GLP-1 Agonists for T2D

The results suggest that dipeptidyl peptidase-4 (DDP-4) inhibitors, which are widely prescribed in Germany, are not a cost-effective option despite lower drug pricing compared with empagliflozin.
Monthly Prescribing Reference

Depression Risk Lower With GLP-1 Receptor Agonists vs DPP-4 Inhibitors in Seniors

Researchers found that the rate difference of depression was 3.48 per 1000 person-years between GLP-1 RA users and SGLT-2i users. HealthDay News — For older adults with type 2 diabetes (T2D), use of ...
TCTMD

Fewer MACE in Diabetic Patients Taking SGLT2 Inhibitors vs DPP-4 Inhibitors

Across a broad swath of patients, short-term use of a sodium-glucose cotransporter 2 (SGLT2) inhibitor appears to reduce the risk of major adverse cardiovascular events, most notably cardiovascular ...
The New England Journal of Medicine

Dipeptidyl Peptidase 4 Inhibition for Prophylaxis of Acute Graft-versus-Host Disease

Dipeptidyl peptidase 4 (DPP-4; also known as CD26), a transmembrane receptor expressed on T cells, has a costimulatory function in activating T cells. In a mouse model, down-regulation of CD26 ...