When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...
Researchers found that cancer cells may repair chemotherapy-induced DNA damage, helping explain treatment resistance in ...
A new review highlights how human evolution has shaped the presence of pathogenic variations in DNA damage repair (DDR) genes, offering a new perspective on why modern populations face increased ...
When it comes to cancer, tumor suppressor genes are usually thought of as the "good guys." These genes make proteins that ...
A new study suggests the APOE2 longevity gene may protect the brain from Alzheimer's by helping neurons repair DNA damage and ...
The APOE2 gene variant protects against Alzheimer's by enhancing DNA repair and preventing neuronal senescence.
Chemotherapy drugs like doxorubicin and etoposide work by snapping a cancer cell’s DNA in two. The breaks are supposed to be ...
RNA’s Surprising Role in DNA Repair New insights could lead to improved treatments for cancer and other diseases. Francesca Storici and her research team discovered a surprising role for RNA in DNA ...
Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal metabolic processes or external stressors such as radiation or chemical ...
The human genome consists of 3 billion base pairs, and when a cell divides, it takes about seven hours to complete making a copy of its DNA. That's almost 120,000 base pairs per second. At that ...
The study focused on rare DNA damage-repair (DDR) disorders, including Ataxia-Telangiectasia (A-T) and Bloom syndrome. These ...