Rocatinlimab, targeting the OX40 pathway, shows significant efficacy in moderate to severe atopic dermatitis, marking a new therapeutic class in disease management. Long-term melanoma data reveal ...

Activation of immune blood biomarkers from interferon gamma pathway distinguished long-term survivors (>=2 years) ...

The placebo-controlled, double-blind, randomised Phase I trial involved 100 healthy participants.

Cohort 4 data demonstrated positive safety and efficacy results, including additional clinical benefit observed following ...

Explore the unique mechanisms of bispecific antibodies and their rapid availability compared to CAR T-cell therapies in cancer treatment.

In today’s ACT Brief, we examine how large de-identified datasets are reshaping trial design and site strategy, why global ...

The new approach brings research directly to participants using decentralised and patient-centric digital engagement tools.

In a new pilot feasibility study, researchers from Mayo Clinic, the University of Washington School of Medicine, the ...

FDA proposes framework clinical trial designs to guide Bayesian methods, improving efficiency in drug development for rare and pediatric conditions.

By Nancy Lapid Jan 22 (Reuters) - Many patients using highly effective GLP-1 drugs like Wegovy may not regain lost weight ...