Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment ...

A molecule that helps regulate gene activity has also been shown to drive skin cancer growth and tumors' ability to evade ...

Siglec-15 has traditionally been understood as an immune checkpoint molecule, primarily located on the cell membrane where it suppresses T-cell function. However, the new research revealed that in SHH ...

A new study published by Mayo Clinic researchers suggests that ovarian cancer cells quickly activate a survival response ...

Druggable phosphatases in cancer and immune cells, with examples of their corresponding drugs. Structures of allosteric inhibitors targeting PP2A, PRL3, DUSP1/6, and SHP2 in cancer cells (left).

Scientists have discovered why ovarian cancer spreads so rapidly through the abdomen. Cancer cells enlist normally protective abdominal cells, forming mixed groups that work together to invade new ...

MINNEAPOLIS/ST. PAUL (07/10/2025) — A University of Minnesota Medical School-led research team discovered that a cancer signaling pathway has previously unrecognized roles in retina and brain blood ...

After months of shrinking scans, the tumors suddenly came roaring back. Oncologists have seen this pattern for years in ...

A new study published by Mayo Clinic researchers suggests that ovarian cancer cells quickly activate a survival response after PARP inhibitor treatment, and blocking this early response may make this ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...