Brendan Jones Ph.D., Xianfeng Morgan Xu, Ph.D. The past week was a truly remarkable week for the CRISPR gene editing field. New developments have reshaped both the legal and scientific landscapes for ...

Mouse embryonic stem cells differentiated into motor neurons after a GFP tag was inserted in frame with the motor-neuron-specific transcription factor HB9, using CRISPR/Cas9 engineering. The Patent ...

Amanda McQuade and Nathaniel Robichaud discuss how integrated proteomic and transcriptomic profiling can reveal cellular responses to genetic perturbations that are not captured through RNA analysis ...

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

The Parties – Senior Party Broad Institute, Harvard University, and MIT (collectively, “Broad”) and Junior Party Regents of the University of California, Berkeley; University of Vienna; and Emmanuelle ...

CRISPR screens generate actionable insights for drug discovery—explore how to optimize a screen, how to avoid pitfalls, and ...

Study identifies a new set of genes and cellular pathway that play a role in the risk of developing Parkinson’s disease Scientists searched the entire human genome using CRISPR interference technology ...

CREME is a virtual laboratory that allows scientists to simulate specific decreases in gene activity. It offers a powerful new tool for identifying and understanding important parts of the genome. And ...