Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

Even as biomedical engineer Anirban Sen Gupta refines artificial platelets to stem traumatic bleeding, he and his colleagues are seeking new uses for their synthetic solution. The latest application ...

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and ...

How Does It Work for ITP? There is no cure for ITP. Its symptoms can vary from person to person, with some people not having any symptoms. Because ITP causes low platelets, the main side effects that ...

PHILADELPHIA – More than half of patients in a Phase III clinical trial who received a limited course of the experimental monoclonal antibody ianalumab for primary immune thrombocytopenia (ITP), an ...

Uncontrolled bleeding represents one of the most alarming medical situations people encounter. While minor cuts and scrapes typically stop bleeding within minutes, persistent bleeding despite proper ...

Glanzmann thrombasthenia (GT) is a rare blood clotting disorder. It’s caused by genetic mutations that affect your platelets, and it can make you more prone to excess bleeding. Chances are, you don’t ...

Essential thrombocythemia (ET) is a type of myeloproliferative neoplasm (MPN), a rare blood disorder that causes an increase in the number of blood cells. Some symptoms include headaches, dizziness, ...